«Dopamine» is a drug which has vasodilatory and cardiotonic action. In addition, it contributes to high blood pressure and increases the secretion of urine. Used in cardiology and toxicology. Administered only intravenously. Contra-indications may cause side effects. Be careful to apply it with other drugs as it is incompatible with many.
The content of the article
- Method of application
- Side effects
«Dopamine» is available in the form of a concentrate for the preparation of the injection. The active substance acts as dopamine hydrochloride. On pharmacy shelves, the buyers can see the drug with dosages of 5, 10, 20 and 40 mg.
The drug is injected into a vein very slowly. Rather quickly absorbed, almost instantly has a therapeutic effect, so it can be used as a «first aid». Is broken down in the liver and kidneys. Starts to be excreted from the blood after 2 minutes, and from the body – in 9 minutes. The process of excretion occurs through the kidneys and takes about 24 hours.
«Dopamine» is actively used in cardiogenic shock, acute heart failure, hypotension. Use it to restore blood volume after suffering the shock of different etiologies.
On the background of poisoning, the patient produces toxins that are excreted in the urine. It is for urine production and meets the drug.
«Dopamine» can not be used for:
- the presence of hormonal tumors pheochromocytoma;
- hypertrophic cardiomyopathy occurs when thickening of the right ventricle;
- fibrillation of the heart;
- myocardial infarction;
- the abnormal heart rhythms;
- low serotonin levels;
- bronchial asthma;
- an excess or deficit of thyroid hormones;
- the presence of serious diseases of the brain.
Do not prescribe this drug to pregnant women because the active substance has the ability to penetrate the placental barrier. Also dopamine hydrochloride is contraindicated during breast-feeding because it is excreted in breast milk and has a negative impact on the child. In Pediatrics this cardiotonic drug is not used.
You should not take the drug in case of hypersensitivity to the components. Be wary appoint it at reduced hemoglobin.
Method of application
«Dopamine» is administered intravenously. The dose is selected by your doctor. To get the solution concentrate is diluted with sodium chloride, 5% dextrose solution, sodium lactate and ringer’s lactate. The preparation of medicines should be carried out before the introduction. The resulting solution should be colorless like water.
Dopamine hydrochloride may cause unwanted effects on the part of the cardiovascular system, manifested as angina, increased or slow heart rhythms, increase or decrease pressure, arrhythmias, and vasospasm.
Some patients reported the nausea, vomiting, headache, increased anxiety, shortness of breath. In rare cases, bronchospasm was observed.
«Dopamine» may cause allergic reactions which require immediate antihistamine treatment.
With alcohol the drug is incompatible, as alcoholic beverages increase the risk of irreversible effects.
The cost of 10 ampoules of «Dopamine» at a dosage of 5 mg is about 60 rubles. The pharmacy can buy the following analogs «Dopamine», «Norepinephrine». The analogues presented in the form of solutions, tablets such drugs are not available.